What It Is and How It's Used
CRISPR or Clustered Regulatory Interspaced Short Palindromic Repeats is a bacterial defense mechanism that forms CRISPR-Cas9. CRISPR is a guided RNA strand inserted to make a cut in the exact location of mutated DNA. CRISPR is used to target a certain section of a gene in a cell and cut out or edit that section. Using CRISPR allows people to permanently change a living cell or organism making it free from disease or infection.
In the diseases listed above, CRISPR can be used to cure and/or minimize the problems formed from each specific disease. DNA is the genetic information in a cell and in each of these diseases the DNA is mutated at some point in the strand. In Pancreatic Cancer CRISPR can be inserted in the cell and remove mutated sections of Chromosomes 9, 12, 17, and 18 if those specific chromosomes are mutated so that the Cancer has less of a chance of growing so rapidly. In Leigh Syndrome it is able to remove the mutated section of Chromosome 9 as well as the mutated genes in the mitochondrial DNA that cause the disease. In Tay-Sachs disease removing the mutated section of HEXA gene could give correct instructions to produce the appropriate enzymes. Also Viral infections can be rendered ineffective by using CRISPR to seek out and cut the foreign DNA in half so the virus cannot reproduce. Once all of these diseases have been removed from the cell premade, clean DNA will be injected into the cell where the mutated DNA was removed. This can be done by inserting the new DNA into a adeno-associated virus, a virus that has no effect on humans, and then inserting the virus into the cell. Although this process might not completely cure each disease it will minimize it or cause it to have less of an effect on the body.
In the diseases listed above, CRISPR can be used to cure and/or minimize the problems formed from each specific disease. DNA is the genetic information in a cell and in each of these diseases the DNA is mutated at some point in the strand. In Pancreatic Cancer CRISPR can be inserted in the cell and remove mutated sections of Chromosomes 9, 12, 17, and 18 if those specific chromosomes are mutated so that the Cancer has less of a chance of growing so rapidly. In Leigh Syndrome it is able to remove the mutated section of Chromosome 9 as well as the mutated genes in the mitochondrial DNA that cause the disease. In Tay-Sachs disease removing the mutated section of HEXA gene could give correct instructions to produce the appropriate enzymes. Also Viral infections can be rendered ineffective by using CRISPR to seek out and cut the foreign DNA in half so the virus cannot reproduce. Once all of these diseases have been removed from the cell premade, clean DNA will be injected into the cell where the mutated DNA was removed. This can be done by inserting the new DNA into a adeno-associated virus, a virus that has no effect on humans, and then inserting the virus into the cell. Although this process might not completely cure each disease it will minimize it or cause it to have less of an effect on the body.